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Carmela Silvestri Selected Research

RNAIII inhibiting peptide

6/2008RNAIII-inhibiting peptide enhances healing of wounds infected with methicillin-resistant Staphylococcus aureus.
12/2007RNAIII-inhibiting peptide affects biofilm formation in a rat model of staphylococcal ureteral stent infection.
9/2006RNAIII-inhibiting peptide in combination with the cathelicidin BMAP-28 reduces lethality in mouse models of staphylococcal sepsis.
1/2006RNAIII-inhibiting peptide significantly reduces bacterial load and enhances the effect of antibiotics in the treatment of central venous catheter-associated Staphylococcus aureus infections.
2/2005RNAIII-inhibiting peptide improves efficacy of clinically used antibiotics in a murine model of staphylococcal sepsis.

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Carmela Silvestri Research Topics

Disease

28Infections
05/2014 - 10/2003
21Sepsis (Septicemia)
12/2011 - 01/2004
10Staphylococcal Infections
08/2013 - 10/2003
8Septic Shock (Toxic Shock Syndrome)
10/2008 - 01/2004
7Wounds and Injuries (Trauma)
05/2014 - 01/2008
7Bacteremia
11/2007 - 02/2005
4Infertility (Sterility)
12/2013 - 07/2008
4Wound Infection (Wound Infections)
10/2013 - 01/2008
3Peritonitis
07/2010 - 01/2008
3Pseudomonas Infections
12/2008 - 12/2007
3Body Weight (Weight, Body)
09/2008 - 07/2004
3Catheter-Related Infections
09/2006 - 10/2005
2Surgical Wound
01/2012 - 04/2008
2Obstructive Jaundice (Cholestatic Jaundice)
11/2006 - 09/2006
1Burns
01/2012
1Gram-Negative Bacterial Infections
12/2008
1Neutropenia
10/2008
1Intraabdominal Infections
01/2008
1Endotoxemia
09/2006
1Surgical Wound Infection
11/2005
1Pneumonia (Pneumonitis)
03/2005
1Shock
02/2005
1Necrosis
09/2004

Drug/Important Bio-Agent (IBA)

22Anti-Bacterial Agents (Antibiotics)IBA
05/2014 - 07/2004
8Antimicrobial PeptidesIBA
12/2008 - 12/2004
7VancomycinFDA LinkGeneric
07/2008 - 10/2003
6Peptides (Polypeptides)IBA
12/2011 - 01/2004
6CathelicidinsIBA
09/2006 - 01/2004
5ImipenemFDA Link
12/2013 - 07/2004
5TeicoplaninIBA
10/2013 - 12/2007
5Tigecycline (Tygacil)FDA Link
08/2013 - 07/2010
5Rifampin (Rifampicin)FDA LinkGeneric
07/2012 - 06/2006
5RNAIII inhibiting peptideIBA
06/2008 - 02/2005
5temporinIBA
04/2008 - 08/2004
5Linezolid (Zyvox)FDA Link
11/2007 - 10/2003
5EndotoxinsIBA
11/2006 - 01/2004
4pexigananIBA
12/2013 - 09/2004
4DaptomycinFDA Link
10/2013 - 09/2011
4Polyethylene Terephthalates (Polyethylene Terephthalate)IBA
08/2013 - 10/2003
4SolutionsIBA
07/2012 - 07/2004
4Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric
12/2011 - 12/2007
4BMAP-28IBA
07/2008 - 12/2004
4GlycopeptidesIBA
04/2007 - 10/2003
3antimicrobial peptide IB-367 (iseganan)IBA
05/2014 - 11/2007
3AgarIBA
08/2013 - 06/2007
3Clarithromycin (Biaxin)FDA LinkGeneric
06/2011 - 11/2005
3Colistin (Coly-Mycin)FDA Link
04/2011 - 11/2005
3Tachypleus tridentatus tachyplesin peptideIBA
12/2008 - 12/2007
3LipopolysaccharidesIBA
01/2008 - 07/2006
3MagaininsIBA
11/2005 - 09/2004
2Methicillin (Metin)FDA Link
10/2013 - 12/2011
2Vitamin EFDA LinkGeneric
12/2011 - 09/2011
2Amikacin (A.M.K)FDA LinkGeneric
06/2011 - 11/2005
2thanatinIBA
04/2011 - 07/2010
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2008 - 01/2008
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2008 - 01/2008
2distinctinIBA
09/2008 - 04/2007
2LipopeptidesIBA
06/2007 - 01/2007
2ExotoxinsIBA
09/2006 - 02/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2006 - 09/2004
2Anti-Infective Agents (Microbicides)IBA
11/2005 - 12/2004
2Ciprofloxacin (Cipro)FDA LinkGeneric
11/2005 - 10/2005
2HistatinsIBA
03/2005 - 07/2004
1Therapeutic UsesIBA
10/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2012
1CopperIBA
01/2012
1CL 331002 (glycylcycline)IBA
01/2012
1Tetracycline (Achromycin)FDA LinkGeneric
01/2012
1buforin IIIBA
04/2009
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
10/2008
1antineoplaston A10 (A 10)IBA
07/2008
1allevynIBA
06/2008
1hamamelitanninIBA
05/2008
1Pharmaceutical PreparationsIBA
05/2008
1indolicidinIBA
01/2008
1Pal-Lys-Lys-NH2IBA
06/2007
1lysyllysine (Lys-Lys)IBA
06/2007
1BMAP-27IBA
11/2006
1tritrpticinIBA
08/2006
1Ertapenem (Invanz)FDA Link
08/2006
1PiperacillinFDA LinkGeneric
07/2006
1Minocycline (Cyclops)FDA LinkGeneric
06/2006
1Proteins (Proteins, Gene)FDA Link
05/2006
1AmidesIBA
11/2005
1Ceftazidime (Fortum)FDA LinkGeneric
11/2005
1quinupristin-dalfopristin (Synercid)FDA Link
10/2005
1Polymyxin B (Aerosporin)FDA LinkGeneric
07/2004
1Sodium ChlorideFDA LinkGeneric
07/2004
1P-113DIBA
07/2004

Therapy/Procedure

9Punctures
07/2010 - 01/2004
9Ligation
07/2010 - 01/2004
7Intraperitoneal Injections
10/2008 - 07/2004
6Central Venous Catheters
11/2007 - 10/2005
5Operative Surgical Procedures
12/2013 - 07/2008
5Stents
07/2012 - 12/2007
4Prostheses and Implants (Prosthesis)
08/2013 - 10/2003
4Antibiotic Prophylaxis
07/2012 - 06/2006
4Therapeutics
07/2010 - 01/2007
1Debridement
01/2012
1Drug Therapy (Chemotherapy)
01/2008